心肌酶譜與心肌損傷標(biāo)志物在急性心肌梗死診斷中的價(jià)值

摘要： 目的評(píng)價(jià)心肌酶譜與心肌損傷標(biāo)志物肌鈣蛋白I(cardiac troponin I,cTnI)在急性心肌梗死(acutemyocardial infarction,AMI)發(fā)病早期升高的幅度與在AMI診斷中的動(dòng)態(tài)應(yīng)用價(jià)值。方法對(duì)130例AMI患者進(jìn)行心肌損傷標(biāo)志物cTnI和心肌酶譜在時(shí)間窗口的比較。結(jié)果 cTnI在AMI發(fā)病早期升高的幅度較心肌酶譜顯著,AMI后4h內(nèi)患者血清中cTnI及肌酸激酶同工酶開(kāi)始升高,12～24h各項(xiàng)指標(biāo)達(dá)高峰。結(jié)論聯(lián)合檢測(cè)血清cTnI及心肌酶譜對(duì)AMI的早期診斷具有重要的臨床價(jià)值。
Objective To evaluate the dynamic application value of myocardial zymogram and cardiac markers troponin Ⅰ(cTnI).In the early diagnosis of acute myocardial infarction(AMI),by detecting their increasing level and time window.Methods A total of 130 patients with AMI were chosen by random and their myocardial zymogram and cardiac markers troponin Ⅰ were tested,then their time window were compared.Results The increasing level of cardiac markers cTnI was more remarkable than myocardial zymogram in the early AMI.Serum cTnI and creatine kinase-MB(CK-MB)began to increase 4 hours after AMI and reached their peaks 12 to 24 hours after AMI.Conclusion Detection of serum cTnI and myocardial enzyme simultaneously have important clinical value on the early diagnosis of AMI.