急性重度有機(jī)磷中毒52例臨床研究

摘要： 目的評價(jià)血液灌流聯(lián)合血液透析、阿托品微量泵持續(xù)泵入治療急性重度有機(jī)磷中毒(acute severeorganophosphorus pesticide poisoning,ASOPP)的臨床應(yīng)用價(jià)值。方法對104例ASOPP患者進(jìn)行回顧性分析,所有患者均給予洗胃等治療,治療組在對照組基礎(chǔ)上加用血液灌流聯(lián)合血液透析、阿托品微量泵治療,比較2組各項(xiàng)臨床資料。結(jié)果治療組昏迷至清醒時(shí)間、阿托品總量、膽堿酯酶恢復(fù)時(shí)間等明顯優(yōu)于對照組,治愈率為84.6%。結(jié)論應(yīng)用血液灌流聯(lián)合血液透析、阿托品微量泵治療ASOPP效果較好。
Objective To evaluate the clinical application of hemoperfusion combined with hemodialysis and continuous micropump infusion of atropine in the treatment of acute severe organophosphorus pesticide poisoning(ASOPP).Methods A total of 104 patients with ASOPP were retrospectively analysed,all patients were treated with gastric lavage and so on,the treated group adopted hemoperfusion combined with hemodialysis and continuous micropump infusion of atropine in addition to basic therapy.The clinical data was compared.Results The treated group was superior to the control group in time from coma to consciousness,total amount of atropine and recovery time of cholinesterase etc.The recovery rate was 84.6%.Conclusion It is effective to apply hemoperfusion combined with hemodialysis and continuous micropump infusion of atropine in rescuing the acute severe organophosphorus pesticide poisoning.